E-ISSN 2578-7322
 

Original Research 


Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats

Victoria Chinenye Obinna, Hope Delesi Kagbo, Gabriel Ogaba Agu.

Cited by (1)

Abstract
Objectives: To supply scientific information / literature on the use of P.oleracea in enhancing fertility in males; either to validate or to refute this folkloric use. This study investigated the effect of the lipophilic and hydrophilic leaf extracts of Portulaca oleracea on male reproductive parameters.
Methods: The extracts were obtained using two extracting solvents chloroform and 80% aqueous methanol in succession. Experimental animals were randomly divided into 7 groups of 16 rats each. Group A (control) received 0.5ml 20% Tween 80 (vehicle), groups B, C and D received 125, 250 and 500 mg/kg of the lipophilic extract respectively and E, F and G received 125, 250 and 500 mg/kg of the hydrophilic extract respectively for 60 days. On days 14, 28, 42 and 60; four rats from each group were weighed and anaesthetized for sample collection. Blood (for testosterone), testes (weight and histomorphology) and sperm cells from caudal epididymis (for semen analysis) were collected.
Results: Both extracts had no significant (p>0.05) effect on testicular weight and histomorphology, and sperm cell characteristics but caused a significant (p<0.05) increase in sperm count. Only the hydrophilic extract produced a significant (p<0.05) reduction in the testosterone level.
Conclusion: Leaf extracts of P.oleracea as used in this study improved spermatogenesis irrespective of the decline in testosterone level. This may justify the use of P.oleracea leaf extracts in enhancing fertility in males, although further studies are required to elucidate the mechanism and compounds associated with these properties.
extracts in enhancing fertility in males, although further studies are required to elucidate the mechanism and compounds associated with these properties.

Key words: Portulaca oleracea, sperm cell count, testosterone, testis, sperm morphology


 
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This Article Cited By the following articles

Lipophilic and hydrophilic leaf extracts of Portulaca oleracea (Purslane) disrupts female sex hormones in albino rats (Rattus norvegicus)
Journal of Traditional and Complementary Medicine 2019; (): .

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How to Cite this Article
Pubmed Style

Obinna VC, Kagbo HD, Agu GO, . Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats. A J Physiol Biochem Pharmacol. 2019; 9(1): 21-32. doi:10.5455/ajpbp.20190124101830


Web Style

Obinna VC, Kagbo HD, Agu GO, . Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats. http://www.ajpbp.com/?mno=27829 [Access: January 28, 2020]. doi:10.5455/ajpbp.20190124101830


AMA (American Medical Association) Style

Obinna VC, Kagbo HD, Agu GO, . Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats. A J Physiol Biochem Pharmacol. 2019; 9(1): 21-32. doi:10.5455/ajpbp.20190124101830



Vancouver/ICMJE Style

Obinna VC, Kagbo HD, Agu GO, . Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats. A J Physiol Biochem Pharmacol. (2019), [cited January 28, 2020]; 9(1): 21-32. doi:10.5455/ajpbp.20190124101830



Harvard Style

Obinna, V. C., Kagbo, . H. D., Agu, . G. O. & (2019) Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats. A J Physiol Biochem Pharmacol, 9 (1), 21-32. doi:10.5455/ajpbp.20190124101830



Turabian Style

Obinna, Victoria Chinenye, Hope Delesi Kagbo, Gabriel Ogaba Agu, and . 2019. Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats. American Journal of Physiology, Biochemistry and Pharmacology, 9 (1), 21-32. doi:10.5455/ajpbp.20190124101830



Chicago Style

Obinna, Victoria Chinenye, Hope Delesi Kagbo, Gabriel Ogaba Agu, and . "Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats." American Journal of Physiology, Biochemistry and Pharmacology 9 (2019), 21-32. doi:10.5455/ajpbp.20190124101830



MLA (The Modern Language Association) Style

Obinna, Victoria Chinenye, Hope Delesi Kagbo, Gabriel Ogaba Agu, and . "Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats." American Journal of Physiology, Biochemistry and Pharmacology 9.1 (2019), 21-32. Print. doi:10.5455/ajpbp.20190124101830



APA (American Psychological Association) Style

Obinna, V. C., Kagbo, . H. D., Agu, . G. O. & (2019) Effects of Lipophilic and Hydrophilic leaf extracts of Portulaca oleracea Linn. (Purslane) on male reproductive parameters in albino rats. American Journal of Physiology, Biochemistry and Pharmacology, 9 (1), 21-32. doi:10.5455/ajpbp.20190124101830





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