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Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India

Anuck Islary, Jatin Sarmah, Sanjay Basumatary.

Cited by (5)

Abstract
Aim: The aim of present study was to investigate the nutritional composition, phytochemical constituents and in vitro antioxidant activities of a wild edible fruit in order to document data for further basic research needs or to widen its use among common people. Methods: The fresh fruits of Grewia sapida Roxb. ex DC. were collected from the Chirang district of Bodoland Territorial Area Districts of Assam, identified and freeze dried. Proximate composition, minerals content and phytochemical constituents were analyzed following standard and reported methods. The antioxidant activities of methanol extract were evaluated by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and 2, 2'-Azinobis (3-ethylbenothiazoline-6-sulfonic acid) diammonium salt (ABTS) assays. Results: The results obtained were reported and discussed. The phytochemical screening of different solvent extracts revealed that fruits contained a number of medicinally active secondary metabolites. The study showed antioxidant properties having IC50 value of 257.666 2.516 μg/mL (DPPH) and 134.33 4.041 μg/mL (ABTS). The total phenolic and flavonoid contents in G. sapida fruit were found to be 294.353 4.696 mg GAE/g dried extract and 116.95 10.71 mg QE/g dried extract respectively. Conclusion: The study suggests that G. sapida fruit could be a good source of minerals and natural antioxidants, and studied further for its beneficial effect in human health.

Key words: Grewia Sapida, proximate composition, mineral contents, phytochemical analysis, antioxidant activity, DPPH, ABTS, North-East India.


 
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REFERENCES
1. Deshmukh BS, Waghmode A. Role of wild edible fruits as a food resource: Traditional knowledge. Int. J. Pharm. Life Sci. 2011;2(7): 919-924.
2. Eromosele IC, Eromosele CO, Kuzhkzha DM. Evaluation of mineral elements and ascorbic acid contents in fruits of some wild plants. Plant Food. Hum. Nutr. 1991;41: 151-154. [DOI via Crossref]    [Pubmed]   
3. Nazarudeen A. Nutritional composition of some lesser-known fruits used by ethnic communities and local folks of Kerala. Indian J. Tradit. Knowl. 2010;9(2): 398-402.
4. Aberoumand A, Deokule SS. Studies on nutritional values of some wild edible plants from Iran and India. Pak J Nutr. 2009;8: 26-31. [DOI via Crossref]   
5. Garcia-Salas P, Morales-Soto A, Segura-Carretero A, FernándezGutiérrez A. Phenolic-Compound-Extraction Systems for Fruit and Vegetable Samples. Molecules 2010;15: 8813-8826. [DOI via Crossref]    [Pubmed]   
6. Narzary H, Brahma S, Basumatary S. Wild edible fruits of Kokrajhar district of Assam, North-East India. Asian J. Plant Sci. Res. 2013;3(6): 95-100.
7. Khomdram S, Barthakur S, Devi GS. Biochemical and molecular analysis of wild endemic fruits of the Manipur region of India. International Journal of Fruit Science 2014;14: 1-14. [DOI via Crossref]   
8. Lee K, Lee HJ, Lee CY. Vitamins, Phytochemicals, Diets, and Their Implementation in Cancer Chemoprevention. Critical Reviews in Food Science and Nutrition 2004;44: 437-452. [DOI via Crossref]    [Pubmed]   
9. Rao AV, Ali A. Biologically Active Phytochemicals in Human Health: Lycopene. International Journal of Food Properties 2007;10: 279-288. [DOI via Crossref]   
10. Sanda MA, Zengin G, Aktumsek A, Cakmak YS. Evaluation of antioxidant potential of two Daphne species (D. gnidioides and D. pontica) from Turkey. Emir. J. Food Agric. 2015;27(6): 488-494. [DOI via Crossref]   
11. Gujral HS, Angurala M, Sharma P, Singh J. Phenolic Content and Antioxidant Activity of Germinated and Cooked Pulses. International Journal of Food Properties 2011;14: 1366-1374. [DOI via Crossref]   
12. Wong JY, Matanjun P, Ooi YBH, Chia KF. Evaluation of Antioxidant Activities in Relation to Total Phenolics and Flavonoids Content of Selected Malaysian Wild Edible Plants by Multivariate Analysis. International Journal of Food Properties 2014;17: 1763-1778. [DOI via Crossref]   
13. Somade OT, Akinloye OA, Adeyeye MO, Fabunmi GD, Idowu OO, Badmus FO, Salaudeen BO. Quercetin, a natural phytochemical and antioxidant protects against sodium azideinduced hepatic and splenic oxidative stress in rats. J Invest Biochem 2015;4(3): 69-74. [DOI via Crossref]   
14. Fu L, Xu BT, Xu XR, Qin XS, Gan RY, Li HB. Antioxidant Capacities and Total Phenolic Contents of 56 Wild Fruits from South China, Molecules 2010;15, 8602-8617. [DOI via Crossref]    [Pubmed]   
15. Stangeland T, Remberg SF, Lye KA. Total antioxidant activity in 35 Ugandan fruits and vegetables. Food Chem. 2009;113: 85-91. [DOI via Crossref]   
16. Suhitha S, Devi SK, Gunasekaran K, Pakyntein HC, Bhattacharjee A, Velmurugan D. Phytochemical Analyses and Activity of Herbal Medicinal Plants of North-East India for Anti-Diabetic, Anti-Cancer and Anti-Tuberculosis and their Docking Studies. Current Topics in Medicinal Chemistry 2015;15(1): 21-36. [DOI via Crossref]    [Pubmed]   
17. Rosangkima G, Rongpi T, Prasad SB. Ethno-medicinal value of some anticancer medicinal plants from north-east India: an in vivo screening in murine tumor model. Sci. Vis. 2010;10(4): 123-132.
18. Haq MZU, Stanković MS, Rizwan K, Feo VD. Grewia asiatica L., a Food Plant with Multiple Uses. Molecules 2013;18: 2663-2682. [DOI via Crossref]    [Pubmed]   
19. AOAC. 2000. Official Methods of Analysis. 17th Ed. Association of Official Analytical Chemists. Inc. Virginia, USA.
20. James CS. 1995. Analytical Chemistry of Foods. 1st Ed. Chapman and Hall, New York. [DOI via Crossref]   
21. FAO. 2003. Food energy-methods of analysis and conversion factors. Food and agriculture organization of the United Nations. FAO Food and Nutrition paper 77. Rome, Italy.
22. Suntornsuk L, Kritsanapun W, Nilkamhank S, Paochom A. Quantitation of vitamin C content in herbal juice using direct titration. Journal of Pharmaceutical and Biochemical Analysis 2002; 28: 849-855. [DOI via Crossref]   
23. Kokate CK. 2005. A Textbook for Practical Pharmacognosy. 5th Ed. Vallabh Prakashan.
24. Ben IO, Woode E, Abotsi WKM, Boakye-Gyasi E. Preliminary Phytochemical Screening and In vitro Antioxidant Properties of Trichilia monadelpha (Thonn.) J. J. de Wilde (Meliaceae). Journal of Medical and Biomedical Sciences 2013;2(2): 6-15.
25. Shukla RK, Painuly D, Porval A, Shukla A. Proximate Analysis, Nutritional Value, Phytochemical Evaluation, and Biological Activity of Litchi chinensis Sonn. Leaves. Journal of Herbs, Spices & Medicinal Plants 2014;20: 196-208. [DOI via Crossref]   
26. Moukette BM, Pieme CA, Njimou JR, Biapa CPN, Marco B, Ngogang JY. In vitro antioxidant properties, free radicals scavenging activities of extracts and polyphenol composition of a non-timber forest product used as spice: Monodora myristica. Biological Research 2015;48: 15. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
27. Zhishen J, Mengcheng T, Jianming W. The determination of flavonoid contents in mulberry and their scavenging effects on Superoxide radicals. Food Chem. 1999;64: 555-559. [DOI via Crossref]   
28. Salih NK-EM, Yahia EM. Nutritional value and antioxidant properties of four wild fruits commonly consumed in Sudan. International Food Research Journal 2015;22(6): 2389-2395.
29. Pareek S. Nutritional composition of jujube fruit. Emir. J. Food Agric. 2013;25(6): 463-470.
30. Lim ASL, Rabeta MS. Proximate analysis, mineral content and antioxidant capacity of milk apple, malay apple and water apple. International Food Research Journal 2013;20(2): 673-679.
31. Gnansounou SM, Noudogbessi JP, Yehouenou B, Sohounhloue D. Proximate composition and micronutrient potentials of Dialium guineense wild growing in Benin. International Food Research Journal 2014;21(4): 1603-1607.
32. Narzary H, Swargiary A, Basumatary S. Proximate and vitamin C analysis of wild edible plants consumed by Bodos of Assam, India. J Mol Pathophysiol 2015;4(4): 128-133. [DOI via Crossref]   
33. Yisa J, Egila JN, Darlinton AO. Chemical composition of Annona senegalensis from Nupe land, Nigeria. African Journal of Biotechnology 2010;9(26): 4106-4109.
34. Patil PD, Chavan NS. A comparative study of nutrients and mineral composition of Carallia brachiata (Lour.) Merill. International Journal of Advances in Scientific Research 2015;1(2): 90-92.
35. Tang YP, Linda BLL, Franz LW. Proximate analysis of Artocarpus odoratissimus (Tarap) in Brunei Darussalam. International Food Research Journal 2013;20(1): 409-415.
36. Seal T, Chaudhuri K. Ethnobotanical importance and nutritional potential of wild edible fruits of Meghalaya state in India. J. Chem. Pharm. Res. 2014;6(10): 680-684.
37. Salunkhe DK, Bolin HR, Reddy NR. 1991. Storage processing and nutritional quality of fruits and vegetables, vol. 1, Fresh fruits and vegetables. CRC Press, Boca Raton. FL.
38. Prakash D, Upadhyay G, Gupta C, Pushpangadan P, Singh KK. Antioxidant and free radical scavenging activities of some promising wild edible fruits, International Food Research Journal 2012;19(3): 1109-1116.
39. Sajib MAM, Jahan S, Islam MZ, Khan TA, Saha BK. Nutritional evaluation and heavy metals content of selected tropical fruits in Bangladesh. International Food Research Journal 2014;21(2): 609-615.
40. Chaturvedi UC, Shrivastava R, Upreti RK. Viral infections and trace elements: A complex interaction. Current Science 2004;87(11): 1536-1554.
41. Meenakshi N, Babu BS, Kumar SP. Analysis of the arsenic in commonly used medicinal plants. Int. J. Ayur. Pharma Research 2014;2(1): 77-83.
42. Haruna SS, Ahmed O, Titilayo JO. Nutritional and anti-nutritional composition of Lantana camara leaf. J Invest Biochem 2015;4(2): 58-60. [DOI via Crossref]   
43. Maisarah AM, Amira BN, Asmah R, Fauziah O. Antioxidant analysis of different parts of Carica papaya. International Food Research Journal 2013;20(3): 1043-1048.
44. Korfali SI, Hawi T, Mroueh M. Evaluation of heavy metals content in dietary supplements in Lebanon. Chemistry Central Journal 2013;7(1): 10. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
45. Mensah JK, Okoli RI, Ohaju-Obodo JO, Eifediyi K. Phytochemical, nutritional and medical properties of some leafy vegetables consumed by Edo people of Nigeria. African Journal of Biotechnology. 2008;7(14): 2304-2309.
46. Bello MO, Asubonteng K, Sodamade A, Adeniyi S. Nutrient potentials of two lesser known leafy vegetables (Vitex doniana L. and Sesamum indicum L.). International Food Research Journal 2014;21(5): 1993-1999.
47. Nair AG, Pradeesh S, Devi CM, Mini I, Swapna TS. Diplazium esculentum: A wild nutrient-rich leafy vegetable from Western Ghats. Prospects in Bioscience 2013;293-301.
48. Islam MZ, Hoque MM, Asif-Ul-Alam SM, Monalisa K. Chemical composition, Antioxidant capacities and storage stability of Citrus macroptera and Garcinia pedunculata fruits. Emir. J. Food Agric. 2015;27(3): 275-282.
49. Arunachalam K, Parimelazhagan T. Evaluation of Phenolic Content, Antioxidant Activity, and Nutritional Composition of Cordia evolutior (Clarke) Gamble. International Journal of Food Properties 2014;17: 226-238. [DOI via Crossref]   
50. Li JW, Fan LP, Ding SD, Ding XL. Nutritional composition of five cultivars of Chinese jujube. Food Chem. 2007;103(2): 454-460. [DOI via Crossref]   
51. Trowbridge F, Martorell M. Forging effective strategies to combat iron deficiency. Summary and recommendations. J. Nutri. 2002;85: 875-880.
52. Ng XN, Chye FY, Ismail AM. Nutritional profile and antioxidative properties of selected tropical wild vegetables. International Food Research Journal 2012;19(4): 1487-1496.
53. Aberoumand A, Deokule SS. Determination of Elements Profile of Some Wild Edible Plants. Food Anal. Methods 2009;2: 116-119. [DOI via Crossref]   
54. Adeyeye EI, Otokiti MKO. Proximate composition and some nutritionally valuable minerals of two varieties of Capsicum annum. (Bell and Cherry peppers). Discovery and Innovation 1999;11: 75-81.
55. Salama AK, Radwan MA. Heavy metals (Cd, Pb) and trace elements (Cu, Zn) contents in some foodstuffs from the Egyptian market. Emir. J. Agric. Sci. 2005;17(1): 34-42. [DOI via Crossref]   
56. Saha J, Biswal AK, Deka SC. Chemical composition of some underutilized green leafy vegetables of Sonitpur district of Assam, India. International Food Research Journal 2015;22(4): 1466-1473.
57. Alinnor IJ, Oze R. Chemical evaluation of the nutritive value of Pentaclethra macrophyllabenth (African oil bean) seeds. Pakistan Journal of Nutrition 2011;10(4): 355-359. [DOI via Crossref]   
58. Pandey G, Jain GC, Mathur N. Therapeutic potential of metals in managing diabetes mellitus: a review. J Mol Pathophysiol 2012;1(1): 63-76. [DOI via Crossref]   
59. Sorenson JR. Copper complexes offer a physiological approach to treatment of chronic diseases. J Prog Med Chem 1989;26: 437-568. [DOI via Crossref]   
60. Saker F, Ybarra J, Leahy P. Glycemia-lowering effect of cobalt chloride in the diabetic rat: role of decreased gluconeogenesis. Am J Physiol Endocrinol Metab 1998;274: E984-E991.
61. Oancea A, Roat ă G, Popescu S, Păun L, Mateescu I, Toma AE, Gaspar A, Sidoroff M. Phytochemical Screening of the Bioactive Compounds in the Most Widespread Medicinal Plants from Calarasi-Silistra Cross-Border Area. Bulletin of the Transilvania University of Bra þov, Series II, 2013;6(55): 135-142.
62. Ramu G, Mohan GK. Preliminary phytochemical and antioxidant study of hydroalcoholic extracts from selected genera of Indian Lamiaceae. Asian Pacific Journal of Tropical Biomedicine 2012;685-688. [DOI via Crossref]   
63. Chidzwondo M, Nyanga F, Zvidzai LK, Mushipe CJ, Muzaka S, Chidewe C. Effects of Processing Methods on Antinutrient Composition of Seeds from A Wild Legume Bauhinia petersiana Sigauke. Asian Journal of Science and Technology 2013;4(4): 012-016.
64. Patel DK, Patel K, Duraiswamy B, Dhanabal SP. Phytochemical analysis and standardization of Strychnos nux-vomica extract through HPTLC techniques. Asian Pacific Journal of Tropical Disease 2012;S56-S60.
65. Yadav RNS, Agarwala M. Phytochemical analysis of some medicinal plants. Journal of Phytology 2011;3(12): 10-14.
66. Liu RH. Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals. Am. J. Clin. Nutr. 2003;78: 517S-520S. [Pubmed]   
67. Nyarko AA, Addy ME. Effects of aqueous extract of Adenia cissampeloides on blood pressure and serum analyte of hypertensive patients. Phytotherapy Res. 1990;4(1): 25-28. [DOI via Crossref]   
68. Vinha AF, Soares MO. Phytochemical characterization and radical scavenging activity of aqueous extracts of medicinal plants from Portugal. European Journal of Medicinal Plants 2012;2(4): 335-347. [DOI via Crossref]   
69. Akachukwu D, Okafor PN, Ibegbulem CO. Phytochemical content of Cnidoscolus aconitifolius and toxicological effect of its aqueous leaf extract in Wistar rats. J Invest Biochem, 2014;[DOI via Crossref]    [DOI via Crossref]   
70. Argal A, Pathak AK. CNS activity of Calotropis gigantea roots. J. Ethnopharmacology. 2006;106: 142-145. [DOI via Crossref]    [Pubmed]   
71. Tiwari P, Kumar B, Kaur M, Kaur G, Kaur H. Phytochemical screening and Extraction: A Review. Internationale Pharmaceuticasciencia 2011;1(1): 98-106.
72. Aruoma OI. Free radicals, oxidative stress and antioxidants in human health and diseases. J. Am. Oil Chemists. Soc. 1998;75: 199-122. [DOI via Crossref]   
73. Shilpa KJ, Krishnakumar G, Sooryaprakash S. Phytochemical Composition, Antioxidant, and Antibacterial Activities of Two Syzygium spp. Journal of Herbs, Spices & Medicinal Plants 2014;20: 45-54. [DOI via Crossref]   
74. Ali SS, Kasoju N, Luthra A, Singh A, Sharanabasava H, Sahuand A, Bora U. Indian medicinal herbs as source of antioxidants. Food Res. 2008;41: 1-15. [DOI via Crossref]   
75. Kostova I, Bhatia S, Grigorov P, Balkansky S, Par-mar VS, Prasad AK, Saso L. Coumarins as antioxidants. Curr Med Chem 2011;18(25): 3929-3951. [DOI via Crossref]    [Pubmed]   
76. Mir AH, Sexena M, Malla MY. Estimation of phenolic and flavonoids content and in vitro antioxidant capacity of Tridex procumbens Linn. (Asteraceae). Int. J. Pharm. Bio. Sci. 2013;4(2): 302-311.
77. Mohsen MS, Ammar SMA. Total phenolic contents and antioxidant activity of corn tassel extracts. Food Chem. 2008;112: 595-598. [DOI via Crossref]   
78. Samappito S, Butkhup L. Analysis of Anthocyanin, Flavonoids, and Phenolic Acid Contents of Ten Fruits and Antioxidant Activity. International Journal of Fruit Science 2010;10: 264-280. [DOI via Crossref]   
79. Akram R, Saqib M, Khalid B, Arshad A. Effects of Extraction Media and Techniques on the Antioxidant Properties and Recovery of Phenolics from Roots of Glycyrrhiza glabra. J Mol Pathophysiol 2015;4(4): 138-143. [DOI via Crossref]   

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How to Cite this Article
Pubmed Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary. Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India. A J Physiol Biochem Pharmacol. 2016; 5(1): 21-31. doi:10.5455/jib.20160422015354


Web Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary. Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India. http://www.ajpbp.com/?mno=215276 [Access: November 12, 2019]. doi:10.5455/jib.20160422015354


AMA (American Medical Association) Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary. Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India. A J Physiol Biochem Pharmacol. 2016; 5(1): 21-31. doi:10.5455/jib.20160422015354



Vancouver/ICMJE Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary. Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India. A J Physiol Biochem Pharmacol. (2016), [cited November 12, 2019]; 5(1): 21-31. doi:10.5455/jib.20160422015354



Harvard Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary (2016) Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India. A J Physiol Biochem Pharmacol, 5 (1), 21-31. doi:10.5455/jib.20160422015354



Turabian Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary. 2016. Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India. American Journal of Physiology, Biochemistry and Pharmacology, 5 (1), 21-31. doi:10.5455/jib.20160422015354



Chicago Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary. "Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India." American Journal of Physiology, Biochemistry and Pharmacology 5 (2016), 21-31. doi:10.5455/jib.20160422015354



MLA (The Modern Language Association) Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary. "Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India." American Journal of Physiology, Biochemistry and Pharmacology 5.1 (2016), 21-31. Print. doi:10.5455/jib.20160422015354



APA (American Psychological Association) Style

Anuck Islary, Jatin Sarmah, Sanjay Basumatary (2016) Proximate composition, mineral content, phytochemical analysis and in vitro antioxidant activities of a wild edible fruit (Grewia sapida Roxb. ex DC.) found in Assam of North-East India. American Journal of Physiology, Biochemistry and Pharmacology, 5 (1), 21-31. doi:10.5455/jib.20160422015354





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